Description

Nsc 19005-D3 is a deuterated chemical compound, specifically a deuterated analog of a key research molecule, identified by CAS No. 244094-71-1. This product is critical for advanced research and development, particularly in pharmaceutical and agrochemical fields where isotopic labeling is required for metabolic, pharmacokinetic, and environmental fate studies. It is primarily needed by R&D scientists, analytical laboratories, and product development teams in the life sciences and specialty chemical sectors seeking high-purity, stable isotope-labeled standards.

Application

• Internal Standard for Mass Spectrometry: Used as a deuterated internal standard in LC-MS and GC-MS analysis for accurate quantification of its non-deuterated counterpart in complex matrices.
• Metabolic Pathway Tracing: Employed in pharmaceutical R&D to trace and elucidate drug metabolism and biotransformation pathways in preclinical studies.
• Pharmacokinetic Studies: Essential for conducting Absorption, Distribution, Metabolism, and Excretion (ADME) studies with high precision and reduced background interference.
• Environmental Fate Analysis: Applied in agrochemical research to study the degradation, translocation, and persistence of active ingredients in environmental samples.
• Biochemical Research: Serves as a tool in mechanistic studies to understand enzyme interactions and reaction mechanisms using isotope effects.
• Quality Control & Method Development: Utilized by analytical laboratories to develop and validate robust analytical methods for impurity profiling and assay determination.

Basic Information

Product Name	Nsc 19005-D3
CAS No.	244094-71-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NSC 19005-D3; 1,3-Dimethyl-8-(trifluoromethyl)-1H-purine-2,6(3H,7H)-dione-d3; Deuterated NSC 19005; 8-(Trifluoromethyl)theophylline-d3; 1,3-Dimethyl-8-(trifluoromethyl)xanthine-d3; 8-Trifluoromethyltheophylline-d3; 8-TFT-d3; Isotopically Labeled Theophylline Derivative
EINECS	Contact for details

Quality Control

Every batch of Nsc 19005-D3 is manufactured and controlled under a strict quality management system. We perform rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity (deuterium incorporation ≥ 98%) and chemical purity (≥ 95% by HPLC). A comprehensive Certificate of Analysis (COA) detailing batch-specific results for identity, purity, and isotopic enrichment is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider keeping the product under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.