Description

H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-Oh, (Disulfide Bond) is a synthetic peptide featuring a critical intramolecular disulfide bridge that stabilizes its bioactive conformation. This compound is of significant interest for its role in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in drug discovery, peptide-based therapeutic studies, and biochemical assay development.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics.
• Biochemical Assays: Used as a ligand or substrate in enzymatic studies, receptor binding assays, and other investigative biochemical protocols.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential drug candidates targeting specific biological pathways.
• Academic & Institutional Research: A valuable tool for universities and research institutes studying protein-protein interactions, peptide structure-activity relationships (SAR), and molecular biology.
• Bioconjugation & Labeling Studies: The reactive thiol groups (post-disulfide reduction) can be utilized for site-specific conjugation with fluorophores, biotin, or other probes.
• Reference Material Production: Acts as a high-purity certified reference material (CRM) for quality control and analytical method validation in regulated environments.

Basic Information

Product Name	H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-Oh, (Disulfide Bond)
CAS No.	244082-19-7
Molecular Formula	C55H75N15O15S2
Molecular Weight	1218.4 g/mol
Synonyms	Cyclo(Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys); Cyclic Cys-T-T-H-W-G-F-T-L-C peptide; CTTHWGFTLC (cyclic); CAS 244082-19-7; H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (Disulfide bridge); Cyclo(CTTHWGFTLC); Cyclic decapeptide with intramolecular disulfide bond
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-Oh, (Disulfide Bond) undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.