Description

(Tetrahydrofuran-3-Yl)Methanesulfonyl Chloride CAS NO 242459-48-9 is a versatile and reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the (tetrahydrofuran-3-yl)methanesulfonyl moiety, a functional group of high interest in medicinal chemistry and materials science. This intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in creating sulfonamide-based molecules with targeted biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific sulfonyl-containing scaffolds.
• Polymer & Materials Science: Acts as a functional monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme activity and protein interactions.
• Ligand & Catalyst Development: Useful for constructing complex ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(Tetrahydrofuran-3-Yl)Methanesulfonyl Chloride
CAS No.	242459-48-9
Molecular Formula	C6H11ClO3S
Molecular Weight	198.67 g/mol
Synonyms	3-(Chlorosulfonylmethyl)tetrahydrofuran; Tetrahydro-3-furanmethanesulfonyl chloride; (Oxolan-3-yl)methanesulfonyl chloride; 3-(Methanesulfonyl chloride)tetrahydrofuran; THF-3-ylmethanesulfonyl chloride; 242459-48-9; (Tetrahydrofuran-3-yl)methanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our (Tetrahydrofuran-3-Yl)Methanesulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.