Description

1,8-Naphthyridin-2-Amine,5,7-Bis(Trifluoromethyl)-n-[3-(Trifluoromethyl)Phenyl]-(9Ci) is a high-value, multi-fluorinated naphthyridine derivative, distinguished by its unique trifluoromethyl-substituted aromatic structure. This compound is engineered to serve as a critical pharmaceutical intermediate and advanced building block in organic synthesis, offering significant potential for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Catalyst Ligand Development: The naphthyridine core can be functionalized to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Item	Information
Product Name	1,8-Naphthyridin-2-Amine,5,7-Bis(Trifluoromethyl)-n-[3-(Trifluoromethyl)Phenyl]-(9Ci)
CAS No.	241488-36-8
Molecular Formula	C₁₈H₁₀F₉N₃
Molecular Weight	463.28 g/mol
Synonyms	5,7-Bis(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]-1,8-naphthyridin-2-amine; N-[3-(Trifluoromethyl)phenyl]-5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amine; 1,8-Naphthyridin-2-amine, 5,7-bis(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]-; 241488-36-8; 5,7-Bis(trifluoromethyl)-2-((3-(trifluoromethyl)phenyl)amino)-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridin-2-Amine,5,7-Bis(Trifluoromethyl)-n-[3-(Trifluoromethyl)Phenyl]-(9Ci) adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.