Description

1,3-Dibromo-2-Methyl-5-(Trifluoromethyl)Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of bromine atoms and a trifluoromethyl group, which serve as key handles for further functionalization via cross-coupling and other metal-catalyzed reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated or brominated aromatic cores for enhanced bioavailability and metabolic stability.
• Agrochemical Active Ingredient Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group imparts desirable properties like lipophilicity and resistance to degradation.
• Material Science & Organic Electronics: Serves as a building block for creating specialized monomers and ligands used in OLED materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to construct complex biaryl and heteroaryl systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on exploring new reaction methodologies and creating compound libraries for screening.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated phosphine or nitrogen-based ligands for asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	1,3-Dibromo-2-Methyl-5-(Trifluoromethyl)Benzene
CAS No.	231953-31-4
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	2,4-Dibromo-6-methyl-α,α,α-trifluorotoluene; 2,4-Dibromo-6-methylbenzotrifluoride; 2-Methyl-1,3-dibromo-5-(trifluoromethyl)benzene; 1,3-Dibromo-2-methyl-5-(trifluoromethyl)benzene; 2,4-Dibromo-α,α,α-trifluoro-m-xylene; Benzene, 1,3-dibromo-2-methyl-5-(trifluoromethyl)-; 2,4-Dibromo-6-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-2-Methyl-5-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.