Description

1-Acetyl-4-Bromo-5(3)-Methyl-3(5)-[Perfluoro(1-Propoxyethyl)]Pyrazole is a specialized fluorinated pyrazole derivative, a high-value building block designed for advanced synthetic chemistry. Its core value lies in the unique combination of a reactive bromine substituent and a perfluoroalkoxy side chain, enabling the precise introduction of fluorine-rich motifs into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorine atoms improve weather resistance, membrane permeability, and biological activity.
• Material Science Research: Serves as a precursor for fluorinated polymers, liquid crystals, or specialty coatings that require specific surface properties and chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions to construct complex, fluorinated heterocyclic systems.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for labeling molecules with fluorine-18 for medical imaging applications.

Basic Information

Product Name	1-Acetyl-4-Bromo-5(3)-Methyl-3(5)-[Perfluoro(1-Propoxyethyl)]Pyrazole
CAS No.	231301-30-7
Molecular Formula	C11H8BrF7N2O2
Molecular Weight	413.09 g/mol
Synonyms	4-Bromo-1-acetyl-5-methyl-3-[perfluoro(1-propoxyethyl)]pyrazole; 1-Acetyl-4-bromo-5-methyl-3-(perfluoro-1-propoxyethyl)pyrazole; 4-Bromo-1-acetyl-5-methyl-3-(perfluoro-1-propoxyethyl)-1H-pyrazole; 1H-Pyrazole, 4-bromo-1-acetyl-5-methyl-3-[2,2,3,3,4,4,4-heptafluorobutoxy]ethyl]-; Perfluorinated Pyrazole Bromide Intermediate; Fluorinated Pyrazole Building Block
EINECS	Contact for details

Quality Control

Our production of 1-Acetyl-4-Bromo-5(3)-Methyl-3(5)-[Perfluoro(1-Propoxyethyl)]Pyrazole adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.