Description

2,4-Dibromo-5-Methylbenzotrifluoride is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique trifluoromethyl and bromine substituents enable precise structural modifications. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a key precursor in the development of advanced herbicides and fungicides, leveraging the biological activity imparted by the trifluoromethyl group.
• Liquid Crystal Materials (LCs): Used in the research and production of fluorinated liquid crystals for display technologies, where it contributes to improved dielectric anisotropy and stability.
• Organic Electronic Materials: Acts as a monomer or intermediate in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine atoms provide excellent handles for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2,4-Dibromo-5-Methylbenzotrifluoride
CAS No.	231285-88-4
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	1,3-Dibromo-4-methyl-2-(trifluoromethyl)benzene; 2,4-Dibromo-α,α,α-trifluoro-5-methyltoluene; 5-Methyl-2,4-dibromobenzotrifluoride; Benzene, 1,3-dibromo-4-methyl-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-1,3-dibromo-4-methylbenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-5-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.