Description

1-(Methoxymethyl)-2-(Trifluoromethyl)Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoromethyl and methoxymethyl substituents, which are key to modulating the lipophilicity, metabolic stability, and electronic properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored optical and electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a versatile synthon for introducing fluorinated aromatic motifs into complex molecular architectures.

Basic Information

Product Name	1-(Methoxymethyl)-2-(Trifluoromethyl)Benzene
CAS No.	227948-39-2
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	2-(Trifluoromethyl)benzyl methyl ether; α-Methoxy-2-(trifluoromethyl)toluene; (2-(Trifluoromethyl)phenyl)methoxymethane; 1-Methoxymethyl-2-trifluoromethylbenzene; o-(Trifluoromethyl)benzyl methyl ether; Benzene, 1-(methoxymethyl)-2-(trifluoromethyl)-; 2-(Trifluoromethyl)benzyl Methyl Ether
EINECS	Contact for details

Quality Control

Our 1-(Methoxymethyl)-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.