Description

4-Fluoro-3-Iodobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and receptor modulator research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and iodine atoms for bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated and iodinated organic electronic materials for displays and lighting.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	4-Fluoro-3-Iodobenzaldehyde
CAS No.	227609-88-3
Molecular Formula	C7H4FIO
Molecular Weight	250.01 g/mol
Synonyms	3-Iodo-4-fluorobenzaldehyde; 4-Fluoro-3-iodo-benzaldehyde; Benzaldehyde, 4-fluoro-3-iodo-; 4-Fluor-3-jodbenzaldehyd; 4-Fluoro-3-iodobenzene-1-carbaldehyde; 3-Iodo-4-fluorobenzenecarboxaldehyde; 4-Fluoro-3-iodo-benzenecarboxaldehyde; 227609-88-3
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Iodobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay, identity, and impurity profiles. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases, reducing agents, and strong oxidizing agents. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.