Description

2-Methyl-5-(Trifluoromethyl)Benzyl Chloride is a versatile and high-value fluorinated aromatic building block. This compound is critical for introducing the benzyl chloride functional group adjacent to a trifluoromethyl moiety, enabling precise molecular modifications. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions, Friedel-Crafts alkylations, and as a precursor to corresponding benzyl alcohols, amines, and ethers.
• Material Science Research: Utilized in creating novel polymers and specialty chemicals with unique surface properties and resistance.

Basic Information

Item	Detail
Product Name	2-Methyl-5-(Trifluoromethyl)Benzyl Chloride
CAS No.	225656-63-3
Molecular Formula	C9H8ClF3
Molecular Weight	208.61 g/mol
Synonyms	1-(Chloromethyl)-2-methyl-5-(trifluoromethyl)benzene; α-Chloro-2-methyl-5-(trifluoromethyl)toluene; 2-Methyl-α,α,α-trifluoro-m-tolyl Chloride; (2-Methyl-5-(trifluoromethyl)phenyl)methyl chloride; 5-(Trifluoromethyl)-2-methylbenzyl chloride; m-Tolyl, 2-methyl-5-(trifluoromethyl)-, chloromethyl deriv.
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-(Trifluoromethyl)Benzyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards for high-purity intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.