Description

4-(3,5-Difluorophenyl)-1-Butene is a high-purity fluorinated organic building block characterized by its phenyl ring substituted with fluorine atoms and a terminal alkene group. This unique structure makes it a versatile intermediate for synthesizing more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl moiety can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic materials, contributing to improved performance in displays.
• Cross-Coupling Reactions: The alkene functionality allows for further functionalization via metathesis, hydrofunctionalization, or polymerization reactions.
• Fluorine Chemistry Research: An important compound for academic and industrial research exploring the effects of fluorine substitution on molecular properties and reactivity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-(3,5-Difluorophenyl)-1-Butene
CAS No.	225240-58-4
Molecular Formula	C10H10F2
Molecular Weight	168.18 g/mol
Synonyms	1-Butene, 4-(3,5-difluorophenyl)-; 3,5-Difluorophenylbutene; 4-(3,5-Difluorophenyl)but-1-ene; (3,5-Difluorophenyl)butene; But-1-en-4-yl-3,5-difluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 4-(3,5-Difluorophenyl)-1-Butene is produced under strict quality management protocols. Our products undergo rigorous quality testing using advanced analytical techniques (including GC, HPLC, NMR, and MS) to ensure identity, purity, and consistency meet the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all critical parameters are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.