Description

4-Ethoxy-3-(5-Methyl-4-Oxo-7-Propyl-3,4-Dihydro-Imidazo[5,1-F][1,2,4]-Triazin-2-Yl)Benzene-Sulfonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates and novel APIs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex sulfonamide and sulfonyl chloride derivatives.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.
• Academic Research: Employed in university and institutional labs for heterocyclic chemistry and drug discovery projects.

Basic Information

Product Name	4-Ethoxy-3-(5-Methyl-4-Oxo-7-Propyl-3,4-Dihydro-Imidazo[5,1-F][1,2,4]-Triazin-2-Yl)Benzene-Sulfonyl Chloride
CAS No.	224789-26-8
Molecular Formula	C₁₇H₁₉ClN₄O₄S
Molecular Weight	410.87 g/mol
Synonyms	4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride; 2-(4-Ethoxy-3-sulfonylchloridophenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one; 224789-26-8; Imidazotriazine sulfonyl chloride derivative; Benzenesulfonyl chloride, 4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)-
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-(5-Methyl-4-Oxo-7-Propyl-3,4-Dihydro-Imidazo[5,1-F][1,2,4]-Triazin-2-Yl)Benzene-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.