Description

Hydroxyvardenafil is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) derivative. This compound is of significant interest for research and development within the pharmaceutical industry, particularly in the study of therapeutic mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers for analytical and process development purposes.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and intermediate in the development of new therapeutic agents.
• Analytical Method Development: Used as a high-purity standard for calibrating HPLC, LC-MS, and other analytical instrumentation in quality control laboratories.
• Process Chemistry & Optimization: Employed in scaling up and refining synthetic pathways for related active pharmaceutical ingredients (APIs).
• Metabolite Studies: Acts as a key compound in pharmacokinetic and metabolic pathway research for related pharmaceuticals.
• Impurity Profiling: Essential for identifying and quantifying related substances and degradation products in final drug formulations.
• Academic & Institutional Research: Used in university and institutional settings for pharmacological and medicinal chemistry studies.

Basic Information

Product Name	Hydroxyvardenafil
CAS No.	224785-98-2
Molecular Formula	C23H32N6O5S
Molecular Weight	504.60 g/mol
Synonyms	2-[2-Ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one; Vardenafil Hydroxy Analog; Vardenafil Metabolite; Vardenafil Related Compound; Hydroxy Vardenafil; 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethylpiperazine; N-Ethylpiperazine sulfonyl derivative of vardenafil.
EINECS	Contact for details

Quality Control

Our Hydroxyvardenafil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.