Description

Vardenafil CAS NO 224785-90-4 is a potent and selective phosphodiesterase type 5 (PDE5) inhibitor, recognized for its high efficacy and specificity. This active pharmaceutical ingredient (API) is critical for the formulation of treatments for erectile dysfunction, offering a reliable therapeutic option. It is primarily required by pharmaceutical manufacturers, research institutions, and compounding facilities engaged in the development and production of prescription medications.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of prescription medications for erectile dysfunction (ED).
• Formulation Development: Used in R&D for creating tablets, orally disintegrating tablets (ODTs), and other solid dosage forms.
• Clinical Research: Serves as a reference standard in bioequivalence studies and pharmacokinetic research.
• Compounding Pharmacy: Utilized by specialized pharmacies for custom medication formulations.
• Generic Drug Production: Essential for manufacturers producing generic versions of branded PDE5 inhibitor drugs.
• Biochemical Research: Used in laboratory studies to investigate PDE5 enzyme inhibition and related cellular pathways.

Basic Information

Product Name	Vardenafil
CAS No.	224785-90-4
Molecular Formula	C23H32N6O4S
Molecular Weight	488.61 g/mol
Synonyms	Vardenafil Hydrochloride; Levitra (trade name); N-[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl-2-ethoxybenzamide; 2-[2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one; BA-21038
EINECS	Contact for details

Quality Control

Our Vardenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets high-purity pharmacopeial standards. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.