Description

4-Chloro-1,2-Dihydro-1-Oxo-7-Isoquinolinesulfonyl Chloride is a high-value, multi-functional chemical intermediate primarily used in advanced organic synthesis. Its core value proposition lies in its dual reactive sites, the sulfonyl chloride and the chlorinated heterocycle, which enable its use as a versatile building block for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: A critical reagent in medicinal chemistry and process chemistry for introducing the isoquinoline sulfonamide pharmacophore.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex heterocyclic dyes and high-performance pigments.

Basic Information

Product Name	4-Chloro-1,2-Dihydro-1-Oxo-7-Isoquinolinesulfonyl Chloride
CAS No.	223671-81-6
Molecular Formula	C9H5Cl2NO3S
Molecular Weight	278.11 g/mol
Synonyms	7-Isoquinolinesulfonyl chloride, 4-chloro-1,2-dihydro-1-oxo-; 4-Chloro-1,2-dihydro-1-oxo-7-isoquinolinesulfonyl chloride; 4-Chloro-1-oxo-1,2-dihydroisoquinoline-7-sulfonyl chloride; 1,2-Dihydro-4-chloro-1-oxo-7-isoquinolinesulfonyl chloride; 4-Chloro-1-oxo-1,2-dihydro-7-isoquinolinesulfonyl chloride; 4-Chloro-1H-isoquinoline-1-one-7-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-1,2-Dihydro-1-Oxo-7-Isoquinolinesulfonyl Chloride adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.