Description

2'-Fluoro-Biphenyl-2-Carbaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a biphenyl core with a strategically placed fluorine atom and an aldehyde functional group, enabling precise chemical modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators that require fluorinated aromatic systems for enhanced activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for constructing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as fluorophores for OLEDs or molecular components for advanced polymers.
• Chemical Biology Probes: Utilized to build fluorescent or affinity tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: Acts as a versatile electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.

Basic Information

Item	Detail
Product Name	2'-Fluoro-Biphenyl-2-Carbaldehyde
CAS No.	223575-95-9
Molecular Formula	C₁₃H₉FO
Molecular Weight	200.21 g/mol
Synonyms	2'-Fluoro[1,1'-biphenyl]-2-carboxaldehyde; 2-(2-Fluorophenyl)benzaldehyde; [1,1'-Biphenyl]-2-carboxaldehyde, 2'-fluoro-; 2-Formyl-2'-fluorobiphenyl; Biphenyl-2-carbaldehyde, 2'-fluoro-; 2'-Fluoro-2-biphenylcarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2'-Fluoro-Biphenyl-2-Carbaldehyde is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. This product is easily oxidized and should be handled with care to minimize exposure to air. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.