Description

2-Pyridinecarboxamide,n-(1,1-Dimethylethyl)-5-Fluoro-(9Ci) is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine atom and pyridine core enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and liquid crystals with specific electronic or optical properties.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and fluorinated analogs in discovery chemistry.
• Ligand Synthesis: Useful for preparing specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its amide and pyridine functional groups.

Basic Information

Product Name	2-Pyridinecarboxamide,n-(1,1-Dimethylethyl)-5-Fluoro-(9Ci)
CAS No.	223444-93-7
Molecular Formula	C10H13FN2O
Molecular Weight	196.22 g/mol
Synonyms	5-Fluoro-N-(tert-butyl)picolinamide; N-tert-Butyl-5-fluoropicolinamide; 5-Fluoro-N-(tert-butyl)pyridine-2-carboxamide; tert-Butyl 5-fluoropyridine-2-carboxamide; 5-Fluoro-2-pyridinecarboxylic acid, N-(1,1-dimethylethyl)amide; 2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-5-fluoro-; 5-Fluoro-N-(tert-butyl)-2-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxamide,n-(1,1-Dimethylethyl)-5-Fluoro-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.