Description

Benzene, 1-(2E)-2-Butenyl-2-Fluoro- (9Ci) is a specialized fluorinated aromatic compound characterized by its unique butenyl side chain. This structural motif makes it a valuable advanced intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where the introduction of fluorine and specific alkyl chains is critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the fluorobenzene core contributes to efficacy and environmental stability.
• Material Science Precursor: Acts as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with tailored electronic or optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and other catalytic transformations to construct more complex, functionalized aromatic systems.
• Fluorine Chemistry Studies: Utilized as a model compound in academic and industrial research to study the effects of fluorine substitution on aromatic reactivity and molecular conformation.

Basic Information

Product Name	Benzene, 1-(2E)-2-Butenyl-2-Fluoro- (9Ci)
CAS No.	222640-87-1
Molecular Formula	C10H11F
Molecular Weight	150.19 g/mol
Synonyms	2-Fluoro-1-[(2E)-2-buten-1-yl]benzene; 1-(2E)-2-Butenyl-2-fluorobenzene; (E)-1-(2-Fluorophenyl)but-2-ene; 2-Fluoro-(E)-1-butenylbenzene; 2-Fluorophenyl-(E)-2-butenyl ether (common misnomer); o-Fluoro-(E)-cinnamylbenzene (analogous name); FBB (abbreviation); E-1-(2-Fluorophenyl)-2-butene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-(2E)-2-Butenyl-2-Fluoro- (9Ci) adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We maintain a quality management system aligned with cGMP principles for API intermediates, and specifications can be developed to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound should be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent potential degradation and handled in accordance with good laboratory practices for organic intermediates.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (area %)
Purity (HPLC)	≥ 96.0%
Isomeric Purity (E/Z Ratio)	≥ 98:2 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.