Description

Elomotecan is a synthetic, small-molecule compound belonging to the class of topoisomerase I inhibitors. This compound matters as a key pharmaceutical intermediate and research chemical in the development of novel anticancer therapeutics. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on oncology drug discovery and development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced investigational anticancer agents.
• Oncology Research: Used as a reference standard or active compound in biochemical and cellular assays to study topoisomerase I inhibition mechanisms.
• Preclinical Development: Employed in formulation studies, pharmacokinetic (PK) modeling, and toxicology assessments for new drug candidates.
• Academic & Institutional Research: Facilitates basic scientific research into DNA replication, repair processes, and apoptosis signaling pathways.
• Process Chemistry & Scale-up: Utilized for developing and optimizing synthetic routes for camptothecin analog production.

Basic Information

Product Name	Elomotecan
CAS No.	220998-10-7
Molecular Formula	C24H23N3O5
Molecular Weight	433.46 g/mol
Synonyms	BN 80927; Elomotecan Hydrochloride (salt form); (S)-10,11-Methylenedioxy-20(S)-camptothecin; 7-[(4-Methylpiperazino)methyl]-10,11-(methylenedioxy)-20(S)-camptothecin; BN80927; BN 80927 dihydrochloride; Topoisomerase I inhibitor BN80927
EINECS	Contact for details

Quality Control

Our Elomotecan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.