Description

Binucleine 2 is a potent and selective small molecule inhibitor of the protein kinase CK2 (Casein Kinase 2). This compound matters for researchers and developers as it provides a critical tool for modulating CK2 activity, a key regulator in numerous cellular processes including cell growth, proliferation, and survival. It is primarily needed by the life sciences sector for applications in biochemical research, pharmaceutical development, and as a reference standard for analytical purposes. Binucleine 2 CAS NO 220088-42-6 is essential for studies in oncology, cell signaling, and drug discovery.

Application

• Biochemical Research: Used as a selective CK2 inhibitor to study kinase signaling pathways, protein phosphorylation, and cellular regulation mechanisms.
• Pharmaceutical R&D: Serves as a lead compound or reference standard in the discovery and development of novel therapeutics targeting CK2-dependent diseases.
• Oncology Studies: Employed in cancer research to investigate the role of CK2 in tumor cell proliferation, apoptosis, and potential therapeutic interventions.
• Cell Biology: A tool for modulating cell cycle progression, DNA repair, and other CK2-mediated cellular functions in vitro.
• Academic Research: Utilized in universities and research institutes for fundamental studies on signal transduction and enzyme kinetics.
• Reference Standard: Acts as a high-purity analytical standard for quality control, method development, and compound identification in laboratory settings.

Basic Information

Product Name	Binucleine 2
CAS No.	220088-42-6
Molecular Formula	C₁₈H₁₈N₄O₂
Molecular Weight	322.36 g/mol
Synonyms	Binucleine 2; 2-(3,4-Dichlorobenzylamino)-4-phenyl-5-(4-pyridyl)-1,3-thiazole; 2-[(3,4-Dichlorophenyl)methylamino]-4-phenyl-5-(4-pyridinyl)-1,3-thiazole; CK2 Inhibitor VIII; Casein Kinase II Inhibitor VIII; 4-Phenyl-2-[(3,4-dichlorobenzyl)amino]-5-(4-pyridyl)thiazole; Bn2
EINECS	Contact for details

Quality Control

Our Binucleine 2 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.