Description

Revexepride is a selective 5-HT4 receptor agonist with significant pharmacological activity. This compound is a key intermediate and active pharmaceutical ingredient (API) in the research and development of novel gastrointestinal prokinetic agents. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of advanced therapeutics targeting motility disorders. The material is supplied under stringent quality controls to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of final drug substances targeting the 5-HT4 receptor.
• Active Pharmaceutical Ingredient (API) R&D: Used directly in preclinical and clinical research for developing new treatments for gastrointestinal disorders such as gastroparesis and chronic constipation.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in vitro and in vivo studies to investigate serotonin receptor pharmacology and signal transduction pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.

Basic Information

Product Name	Revexepride
CAS No.	219984-49-3
Molecular Formula	C23H30N4O3S
Molecular Weight	442.57 g/mol
Synonyms	Revexepride; UNII-0JQ8007U4C; (3S)-3-[(4-Amino-5-chloro-2-methoxyphenyl)methylamino]-1-ethyl-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indole-5-carboxamide; 5-HT4 receptor agonist; Prucalopride Impurity; Benzamide, N-[(1-ethyl-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-3-yl)methyl]-4-amino-5-chloro-2-methoxy-
EINECS	Contact for details

Quality Control

Our Revexepride is manufactured and tested under a strict quality management system. Each batch is released with a comprehensive Certificate of Analysis (COA) confirming identity, purity, and conformance to agreed specifications. We support development and commercial projects with materials suitable for research use and can provide documentation for regulatory filings. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.