Description

Sulamserod is a selective serotonin receptor antagonist with significant pharmacological research interest. This compound matters for its potential role in modulating gastrointestinal motility and related physiological pathways, making it a valuable reference standard and active pharmaceutical ingredient (API) intermediate. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel therapeutic agents targeting serotonin receptors.
• Biochemical Assay Development: Utilized as a selective ligand in receptor binding studies and functional assays to investigate serotonin receptor subtypes.
• Preclinical Studies: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology evaluations in animal models.
• Analytical Method Development: Used as a high-purity standard for calibrating HPLC, LC-MS, and other analytical instruments in quality control laboratories.
• Chemical Synthesis: Acts as a sophisticated building block for medicinal chemists exploring structure-activity relationships (SAR) in drug discovery programs.
• Academic Research: Employed in university and institutional labs for fundamental studies on gastrointestinal physiology and neurotransmitter systems.

Basic Information

Product Name	Sulamserod
CAS No.	219757-90-1
Molecular Formula	C20H23N3O3S
Molecular Weight	385.48 g/mol
Synonyms	4-Amino-5-chloro-2-methoxy-N-[[(4RS,7RS)-7-hydroxy-1-azabicyclo[2.2.2]oct-4-yl]methyl]benzamide; YM-31636; (4-Amino-5-chloro-2-methoxy-N-{[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]methyl}benzamide); UNII-4G1F4V8Y3I
EINECS	Contact for details

Quality Control

Our Sulamserod is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets high-grade research standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.