Description

2-Methoxypyridine-3-Sulfonyl Chloride is a versatile and reactive organosulfur compound, primarily used as a key building block in advanced organic synthesis. Its core value lies in its sulfonyl chloride functional group, which readily undergoes nucleophilic substitution to form sulfonamides and sulfonate esters, making it indispensable for constructing complex molecular architectures. This high-purity intermediate is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfonyl moiety enhances biological activity.
• Material Science Research: Serves as a functionalization agent for modifying polymers and surfaces to impart specific chemical properties.
• Chemical Biology & Proteomics: Acts as a reactive handle in the design of activity-based probes and affinity labels for studying enzyme function.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	2-Methoxypyridine-3-Sulfonyl Chloride
CAS No.	219715-44-3
Molecular Formula	C6H6ClNO3S
Molecular Weight	207.63 g/mol
Synonyms	3-Methoxypyridine-2-sulfonyl chloride; 2-Methoxy-3-pyridinesulfonyl chloride; 3-Pyridinesulfonyl chloride, 2-methoxy-; 2-Methoxypyridine-3-sulfonylchloride; 2-Methoxy-pyridine-3-sulfonyl chloride; 3-Chlorosulfonyl-2-methoxypyridine
EINECS	Contact for details

Quality Control

Our 2-Methoxypyridine-3-Sulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.