Description

2-Methoxy-4-Trifluoromethyl-Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a methoxy group with a trifluoromethyl substituent on the pyridine ring, makes it an essential intermediate for creating molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its fluorine content can enhance metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and materials science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs or semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Methoxy-4-Trifluoromethyl-Pyridine
CAS No.	219715-34-1
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	4-(Trifluoromethyl)-2-methoxypyridine; 2-Methoxy-4-(trifluoromethyl)pyridine; 2-Methoxy-α,α,α-trifluoro-4-picoline; 4-Trifluoromethyl-2-methoxypyridine; 2-Methoxy-4-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Trifluoromethyl-Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical specifications such as assay and impurity profiles. Our commitment to reliable supply and traceability supports your R&D and scale-up processes with confidence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.