Description

3-Ethoxyphenylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis for the formation of carbon-carbon bonds. Its primary value lies in its ability to introduce the 3-ethoxyphenyl moiety into target molecules, enabling the construction of complex chemical architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it serves as a key building block for active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for constructing active pharmaceutical ingredients (APIs), particularly those containing aryl ether functional groups.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides that require specific phenoxy structures for bioactivity.
• Liquid Crystal & OLED Material Production: Serves as a precursor for creating advanced organic electronic materials and display components.
• Fine Chemical & Specialty Polymer Synthesis: Employed in the production of specialty monomers, ligands for catalysis, and performance polymers.
• Academic & Industrial R&D: A fundamental reagent in method development and exploratory chemistry for novel compound libraries.
• Cross-Coupling Reactions: Acts as a nucleophilic coupling partner in reactions such as Kumada coupling for biaryl synthesis.

Basic Information

Product Name	3-Ethoxyphenylmagnesium Bromide
CAS No.	219706-48-6
Molecular Formula	C8H9BrMgO
Molecular Weight	225.36 g/mol
Synonyms	Magnesium, bromo(3-ethoxyphenyl)-; (3-Ethoxyphenyl)magnesium bromide; m-Ethoxyphenylmagnesium bromide; 3-Ethoxybenzenemagnesium bromide; 1-Bromo-3-ethoxybenzene magnesium; Grignard reagent, 3-ethoxyphenylmagnesium bromide; 3-Ethoxy-phenylmagnesium bromide solution
EINECS	Contact for details

Quality Control

Our 3-Ethoxyphenylmagnesium Bromide is manufactured under stringent quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For solutions, typical recommended storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, oxidizers, and protic solvents.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light brown solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Typical)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Purity (GC/HPLC)	Contact for details
Solvent	Specified (Tetrahydrofuran, Diethyl ether, etc.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.