Description

Ethyl 3-(Chlorosulfonyl)Benzoate is a versatile and high-purity organic synthesis intermediate, primarily valued for its dual reactive sites: the chlorosulfonyl group and the ester moiety. This compound is critical for facilitating the construction of complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is an essential building block for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce sulfonamide or sulfonate functionalities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of modern herbicides and fungicides that require a sulfonyl chloride precursor.
• Dyestuff and Pigment Manufacturing: Serves as a reactant for creating sulfonated dyes and colorants with enhanced solubility and fastness properties.
• Polymer Modification: Employed to introduce sulfonyl groups into polymer chains, altering properties like hydrophilicity and ionic character.
• Liquid Crystal & OLED Materials: A precursor in the synthesis of sulfone-containing compounds used in electronic display technologies.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process development in contract research organizations (CROs) and CDMOs.

Basic Information

Product Name	Ethyl 3-(Chlorosulfonyl)Benzoate
CAS No.	217453-46-8
Molecular Formula	C9H9ClO4S
Molecular Weight	248.68 g/mol
Synonyms	3-(Chlorosulfonyl)benzoic acid ethyl ester; Ethyl 3-chlorosulfonylbenzoate; Benzoic acid, 3-(chlorosulfonyl)-, ethyl ester; m-(Chlorosulfonyl)benzoic Acid Ethyl Ester; 3-Carbethoxybenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-(Chlorosulfonyl)Benzoate is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent hydrolysis and degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.