Description

4-Bromo-2-Fluorobenzenesulfonyl Chloride is a high-purity organosulfur building block essential for advanced synthetic chemistry. This compound serves as a critical intermediate for introducing the 4-bromo-2-fluorobenzenesulfonyl moiety into target molecules, enabling the development of novel compounds with specific functionalities. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery, material science, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for functionalized polymers and advanced materials with specific surface properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.
• Ligand & Catalyst Development: Useful for creating novel sulfonyl-containing ligands for catalytic systems.

Basic Information

Product Name	4-Bromo-2-Fluorobenzenesulfonyl Chloride
CAS No.	216159-03-4
Molecular Formula	C6H3BrClFO2S
Molecular Weight	273.50 g/mol
Synonyms	2-Fluoro-4-bromobenzenesulfonyl chloride; 1-Bromo-4-fluoro-2-sulfonylchloridobenzene; 4-Bromo-2-fluorobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-2-fluoro-; 4-Bromo-2-fluorophenylsulfonyl chloride; 2-Fluoro-4-bromophenylsulfonyl chloride; p-Bromo-o-fluorobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluorobenzenesulfonyl Chloride is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and FTIR analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.