Description

Pyridine, 2-Fluoro-4-(Iodomethyl)- (9Ci) is a halogenated pyridine derivative, a versatile and high-value organic building block. This compound is critical for advanced chemical synthesis, offering a reactive iodomethyl handle for cross-coupling and functionalization reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those requiring fluorinated and iodinated motifs for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the pyridine core and halogen substituents are common structural features.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the creation of functionalized organic molecules for advanced materials, such as organic semiconductors or liquid crystals.
• Cross-Coupling Reactions: The iodomethyl group makes it a valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and mechanisms.

Basic Information

Product Name	Pyridine, 2-Fluoro-4-(Iodomethyl)- (9Ci)
CAS No.	215674-15-0
Molecular Formula	C7H7FIN
Molecular Weight	251.04 g/mol
Synonyms	2-Fluoro-4-(iodomethyl)pyridine; 4-(Iodomethyl)-2-fluoropyridine; (2-Fluoropyridin-4-yl)methyl iodide; 2-Fluoro-4-pyridinylmethyl iodide; 215674-15-0; AI3-52335; CTK8G0332; NSC 405124; ZINC000005138761
EINECS	Contact for details

Quality Control

Our Pyridine, 2-Fluoro-4-(Iodomethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature and organic iodide content, it is recommended to handle under an inert atmosphere for long-term stability and to minimize decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.