Description

Afeletecan CAS NO 215604-66-3 is a high-purity pharmaceutical intermediate and active ingredient of significant interest in advanced oncology research and development. This compound is valued for its role as a key synthetic precursor in the production of novel chemotherapeutic agents. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the synthesis of targeted cancer therapies. Our supply ensures the stringent quality and consistency required for critical pharmaceutical applications.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potent camptothecin analog anticancer drugs.
• Oncology Drug Development: Serves as a key precursor in research and development programs for novel topoisomerase I inhibitors.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the final stages of API manufacturing for specific chemotherapeutic compounds.
• Biochemical Research: Employed in laboratory studies to investigate mechanisms of action and structure-activity relationships (SAR) of anticancer agents.
• Process Chemistry & Scale-Up: Supports process optimization and scale-up activities from laboratory to pilot and commercial production scales.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control testing.

Basic Information

Product Name	Afeletecan
CAS No.	215604-66-3
Molecular Formula	C24H23N3O5
Molecular Weight	433.46 g/mol
Synonyms	7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin; 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-CPT; Afeletecan; CKD-602; Belotecan intermediate; Camptothecin analog intermediate; Topoisomerase I inhibitor intermediate
EINECS	Contact for details

Quality Control

Every batch of Afeletecan (CAS 215604-66-3) is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to support regulatory filings and ensure traceability. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.