Description

5-(2-Methyl-1,3-thiazol-4-yl)thiophene-2-sulfonyl chloride is a high-value, multi-functional heterocyclic sulfonyl chloride building block. This compound is critical for the synthesis of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating sulfonamide derivatives with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, potentially for use in antivirals, enzyme inhibitors, or receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides where the thiazole-thiophene scaffold confers specific bioactivity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling or modifying biomolecules due to its sulfonyl chloride group's reactivity with amines and alcohols.
• Material Science Research: Employed in the creation of novel organic electronic materials or metal-organic frameworks (MOFs) where its conjugated system and functional group are advantageous.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving clients in drug discovery and fine chemical production.

Basic Information

Product Name	5-(2-Methyl-1,3-thiazol-4-yl)thiophene-2-sulfonyl chloride
CAS No.	215434-25-6
Molecular Formula	C9H6ClNO2S3
Molecular Weight	307.80 g/mol
Synonyms	5-(2-Methyl-4-thiazolyl)-2-thiophenesulfonyl chloride; 2-Thiophenesulfonyl chloride, 5-(2-methyl-4-thiazolyl)-; 4-(5-Chlorosulfonyl-2-thienyl)-2-methylthiazole; 5-(2-Methylthiazol-4-yl)thiophene-2-sulfonyl chloride; 2-Methyl-4-(5-sulfonylchloridothiophen-2-yl)thiazole
EINECS	Contact for details

Quality Control

Our 5-(2-Methyl-1,3-thiazol-4-yl)thiophene-2-sulfonyl chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.