Description

6-Fluoro-3-Hydroxy-2-Iodopyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by research chemists and process development scientists working on novel active ingredients, where its reactive iodine and fluorine atoms enable precise structural modifications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	6-Fluoro-3-Hydroxy-2-Iodopyridine
CAS No.	214911-10-1
Molecular Formula	C5H3FINO
Molecular Weight	238.99 g/mol
Synonyms	2-Iodo-6-fluoro-3-pyridinol; 3-Hydroxy-2-iodo-6-fluoropyridine; 6-Fluoro-2-iodopyridin-3-ol; 2-Iodo-6-fluoropyridin-3-ol; 6-Fluoro-3-hydroxy-2-iodopyridine; 214911-10-1; 6-Fluoro-2-iodo-3-hydroxypyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-3-Hydroxy-2-Iodopyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and guarantee batch-to-batch consistency to support your regulatory filings and process validation. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profiles via techniques like HPLC, NMR, and MS, is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.