Description

Ent-8-iso-15(S)-Prostaglandin F2α is a synthetic, stereochemically defined analog of the naturally occurring prostaglandin F2α. This compound is a valuable biochemical tool and a critical intermediate in advanced pharmaceutical research, particularly in the study of prostanoid receptor signaling and metabolic pathways. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity, well-characterized reference standards and building blocks for drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug manufacturing.
• Biochemical Research: Serves as a key reagent in studying the biological activity, metabolism, and signaling pathways of prostaglandins and their receptors (FP receptors).
• Drug Discovery & Development: Acts as a sophisticated synthetic intermediate or a lead compound for the development of novel therapeutics targeting inflammation, ocular pressure, and reproductive health.
• Academic Research: Utilized in university and institutional labs for fundamental research in physiology, pharmacology, and medicinal chemistry.
• Metabolite Synthesis: Employed in the synthesis of specific prostaglandin metabolites for diagnostic and research applications.

Basic Information

Product Name	Ent-8-iso-15(S)-Prostaglandin F2α
CAS No.	214748-66-0
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	ent-8-iso-PGF2α; (-)-8-iso-Prostaglandin F2α; 15(S)-8-iso-prostaglandin F2α; 8-iso-PGF2α enantiomer; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid; 8-iso-15S-PGF2α; Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)-
EINECS	Contact for details

Quality Control

Every batch of Ent-8-iso-15(S)-Prostaglandin F2α is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and potency testing using advanced analytical techniques such as HPLC, NMR, and MS to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.