Description

tert-Butyl 4-(Trifluoromethyl)-2-Formylphenylcarbamate is a high-purity, multifunctional chemical intermediate characterized by its phenylcarbamate core and reactive aldehyde group. This compound is valued for its role as a critical building block in advanced organic synthesis, enabling the development of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced polymers and functional materials where specific aromatic and carbamate functionalities are required.
• Custom Synthesis and Contract Manufacturing: An essential substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	tert-Butyl 4-(Trifluoromethyl)-2-Formylphenylcarbamate
CAS No.	212696-38-3
Molecular Formula	C13H14F3NO3
Molecular Weight	289.25 g/mol
Synonyms	tert-Butyl N-[4-(Trifluoromethyl)-2-formylphenyl]carbamate; 2-Formyl-4-(trifluoromethyl)phenyl Carbamic Acid tert-Butyl Ester; 4-(Trifluoromethyl)-2-formylphenylcarbamic Acid tert-Butyl Ester; tert-Butyl (4-(Trifluoromethyl)-2-formylphenyl)carbamate; BOC-4-Trifluoromethylanthranilic Aldehyde; (4-(Trifluoromethyl)-2-formylphenyl)carbamic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Trifluoromethyl)-2-Formylphenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.