Description

6-Fluoro-3,4-Pyridinediamine is a high-purity, multifunctional aromatic amine building block, essential for advanced organic synthesis. Its core value lies in its unique fluorine-substituted pyridine diamine structure, which enables precise molecular modifications critical for developing novel active compounds. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, agrochemical development, and specialty material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used in the development of advanced fungicides, herbicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a versatile building block for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, dyes, and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated heterocyclic amines.

Basic Information

Product Name	6-Fluoro-3,4-Pyridinediamine
CAS No.	212268-13-8
Molecular Formula	C5H6FN3
Molecular Weight	127.12 g/mol
Synonyms	3,4-Diamino-6-fluoropyridine; 6-Fluoro-3,4-diaminopyridine; 6-Fluoropyridine-3,4-diamine; 3,4-Pyridinediamine, 6-fluoro-; 6-Fluoro-pyridine-3,4-diamine; 212268-13-8; 6-Fluoro-3,4-pyridinylenediamine
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3,4-Pyridinediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.