Description

Pyridine, 2-Fluoro-3-(Methylthio)- (9Ci) is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a pyridine core with fluorine and methylthio substituents, which enables precise modulation of electronic and steric properties in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized heterocycles for organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes to study biological mechanisms and interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated pyridine derivatives.

Basic Information

Product Name	Pyridine, 2-Fluoro-3-(Methylthio)- (9Ci)
CAS No.	210992-56-6
Molecular Formula	C7H8FNS
Molecular Weight	157.21 g/mol
Synonyms	2-Fluoro-3-(methylthio)pyridine; 3-(Methylthio)-2-fluoropyridine; 2-Fluoro-3-methylsulfanylpyridine; 2-Fluoro-3-(methylmercapto)pyridine; 2-Fluoro-3-(methylsulfanyl)pyridine; Fluorinated pyridine thioether; 2-F-3-SMe-Pyridine
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 2-Fluoro-3-(Methylthio)- is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by GC, HPLC, and NMR. Our quality system is designed to support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its fluoride/strong alkali chemical property, ensure it is stored separately from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.