Description

15(R)-15-Methyl Prostaglandin D2 is a synthetic analog of the naturally occurring prostaglandin D2, distinguished by a methyl group at the 15(R) position. This structural modification enhances its metabolic stability and receptor selectivity, making it a critical research tool for studying prostanoid signaling pathways. It is primarily utilized by pharmaceutical R&D teams and academic researchers in biochemistry and pharmacology for investigating inflammation, allergic responses, and sleep regulation.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of DP1 and DP2 (CRTH2) receptor pharmacology and signaling cascades.
• Drug Discovery & Development: Serves as a key intermediate or pharmacological probe in the development of novel anti-inflammatory and anti-allergic therapeutics.
• In Vitro & In Vivo Studies: Employed in cellular assays and animal models to elucidate the role of prostaglandin D2 metabolites in physiological and pathological processes.
• Analytical Standard: Used for method development, calibration, and quantification in HPLC, LC-MS, and other analytical techniques within quality control and research laboratories.

Basic Information

Product Name	15(R)-15-Methyl Prostaglandin D2
CAS No.	210978-26-0
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	15(R)-15-Methyl-PGD2; (5Z,13E,15R)-9-Oxo-15-methyl-11α,15-dihydroxyprosta-5,13-dien-1-oic Acid; 15-Methylprostaglandin D2; 15(R)-Methyl PGD2; 15-Me-PGD2; 15(R)-15-Methyl-PG D2
EINECS	Contact for details

Quality Control

Our 15(R)-15-Methyl Prostaglandin D2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis and structural confirmation (NMR, MS), to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and research compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the vial to reach room temperature in a desiccator before opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.