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Alprostadil Ethanolamide CAS NO 210976-81-1


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CAS No.:210976-81-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Alprostadil Ethanolamide is a synthetic derivative of alprostadil, a prostaglandin E1 (PGE1) analog, designed for enhanced stability and specific pharmacological activity. This compound is of significant interest in advanced pharmaceutical research and development due to its potential role in modulating vascular and smooth muscle tone. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for cardiovascular and urological applications. The product is supplied under stringent quality controls to ensure reliability for critical R&D and manufacturing processes.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced prostaglandin-based active pharmaceutical ingredients (APIs).
  • Cardiovascular Research: Used in preclinical studies to investigate vasodilation, platelet aggregation inhibition, and treatments for peripheral arterial diseases.
  • Urological Research: Applied in research models for studying erectile dysfunction and exploring new therapeutic formulations.
  • Cell Signaling Studies: Employed as a tool compound to study prostaglandin receptor (EP receptor) interactions and downstream cellular pathways.
  • Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Drug Delivery System Development: Investigated in the formulation of stable and targeted delivery systems for prostaglandin analogs.

Basic Information

Product Name Alprostadil Ethanolamide
CAS No. 210976-81-1
Molecular Formula C23H37NO6
Molecular Weight 423.55 g/mol
Synonyms PGE1 Ethanolamide; Prostaglandin E1 Ethanolamide; 11α,15α-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid ethanolamide; Alprostadil Monoethanolamide; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid ethanolamide; 13,14-Dihydro-15-keto-PGE1 Ethanolamide (related analog); PGE1-EA
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Quality Control

Our Alprostadil Ethanolamide is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support its use in pharmaceutical applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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