Description

Mcc950 CAS NO 210826-40-7 is a potent and selective small molecule inhibitor of the NLRP3 inflammasome, a key signaling complex involved in the innate immune response. This compound is crucial for researchers and developers targeting inflammatory pathways associated with a wide range of diseases. It is primarily utilized in pharmaceutical R&D, academic research, and the development of novel therapeutics for conditions like autoimmune disorders, neurodegenerative diseases, and metabolic syndromes.

Application

• Pharmaceutical Research & Development: As a critical tool compound for studying NLRP3 inflammasome biology and validating it as a therapeutic target.
• Preclinical Drug Discovery: Used in in vitro and in vivo models to assess the efficacy of NLRP3 inhibition for treating inflammatory and autoimmune conditions.
• Academic & Biomedical Research: Investigating the role of inflammasome activation in diseases such as Alzheimer's, Parkinson's, multiple sclerosis, gout, and type 2 diabetes.
• Biochemical Assay Development: Serving as a reference standard in high-throughput screening (HTS) campaigns to identify new NLRP3 inhibitors.
• Inflammation & Immunology Studies: Exploring mechanisms of sterile inflammation, sepsis, and other immune-mediated pathological processes.

Basic Information

Product Name	Mcc950
CAS No.	210826-40-7
Molecular Formula	C₂₀H₂₃ClN₂O₇S
Molecular Weight	470.92 g/mol
Synonyms	MCC-950; CP-456773; CRID3; NLRP3 Inhibitor; 1-(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea; Sodium Salt of MCC950; Inflammasome Inhibitor
EINECS	Contact for details

Quality Control

Our Mcc950 is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.