Description

Benzene, 1,2-Difluoro-4,5-Diiodo- is a highly functionalized halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile precursor for cross-coupling reactions and the development of complex molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to introduce specific halogen atoms for bioactivity or further functionalization.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates where the fluorine atoms can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the halogenated core for specific biological activity.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where halogenated aromatics tune electronic properties.
• Cross-Coupling Reactions: The iodine atoms are excellent substrates for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira, Heck couplings) to create complex biaryl and conjugated systems.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis or as a core structure in catalyst design.
• Chemical Research & Development: A valuable tool for academic and industrial R&D in exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	Benzene, 1,2-Difluoro-4,5-Diiodo-
CAS No.	210567-10-5
Molecular Formula	C6H2F2I2
Molecular Weight	377.89 g/mol
Synonyms	1,2-Difluoro-4,5-diiodobenzene; 4,5-Diiodo-1,2-difluorobenzene; 1,2-Difluoro-4,5-diiodo-benzene; Benzene, 1,2-difluoro-4,5-diiodo-; 210567-10-5; 4,5-Diiodo-o-difluorobenzene; o-Difluoro-4,5-diiodobenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1,2-Difluoro-4,5-Diiodo- is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.