Description

2,3-Difluorobenzene-1-Sulfonyl Chloride is a versatile and highly reactive organosulfur compound, primarily used as a key sulfonylation reagent in advanced organic synthesis. Its value lies in its ability to introduce the sulfonyl functional group into target molecules, a critical step for modifying physicochemical properties and biological activity. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the sulfonyl moiety enhances efficacy and selectivity.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and advanced materials with tailored properties.
• Chemical Biology Probes: Serves as a reagent for labeling and modifying biomolecules to study protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom chemical synthesis services and process development at scale.

Basic Information

Product Name	2,3-Difluorobenzene-1-Sulfonyl Chloride
CAS No.	210532-24-4
Molecular Formula	C6H3ClF2O2S
Molecular Weight	212.60 g/mol
Synonyms	2,3-Difluorobenzenesulfonyl chloride; 1,2-Difluoro-3-sulfonylchloridobenzene; 2,3-Difluorophenylsulfonyl chloride; Benzenesulfonyl chloride, 2,3-difluoro-; 210532-24-4; 2,3-DFBS-Cl
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluorobenzene-1-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure high purity and consistency. Our products undergo rigorous analytical testing, including HPLC, NMR, and titration methods, to meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) and keep it away from moisture, strong bases, and oxidizing agents. Typical recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.