Description

4-(Methylthio)Phenylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry for the formation of carbon-carbon bonds. Its value lies in its ability to introduce the 4-(methylthio)phenyl moiety into complex molecular architectures, a functional group of significant interest in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material industries seeking to synthesize novel sulfur-containing compounds.

Application

• As a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing aryl thioether functionalities.
• For the preparation of liquid crystal materials and organic electronic compounds where the 4-(methylthio)phenyl group modifies electronic properties.
• In agrochemical research for constructing novel herbicides, fungicides, and insecticides with tailored activity profiles.
• As a reagent in coupling reactions (e.g., Kumada coupling) to create biaryl structures for material science applications.
• For the functionalization of polymers and dendrimers to impart specific chemical or physical characteristics.
• In academic and industrial R&D laboratories for method development and exploring new synthetic pathways.

Basic Information

Item	Detail
Product Name	4-(Methylthio)Phenylmagnesium Chloride
CAS No.	210292-04-9
Molecular Formula	C7H7ClMgS
Molecular Weight	182.95 g/mol
Synonyms	4-(Methylthio)phenylmagnesium chloride; p-(Methylthio)phenylmagnesium chloride; 4-Methylsulfanylphenylmagnesium chloride; (4-Methylsulfanylphenyl)magnesium chloride; Grignard Reagent (4-Methylthiophenyl)MgCl; 4-(Methylmercapto)phenylmagnesium chloride; p-Methylthiophenylmagnesium chloride
EINECS	Contact for details

Quality Control

Our 4-(Methylthio)Phenylmagnesium Chloride is produced and handled under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content, to ensure consistency and reliability for your synthetic applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For prolonged stability, storage at 2-8°C is recommended. Always use appropriate handling techniques to exclude air and moisture.

Specification

Item	Specification
Appearance	Brown to dark brown solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.