Description

Pyridine,3,5-Difluoro-4-(Trimethylsilyl)-(9Ci) is a high-value, multi-functional organosilicon building block characterized by its pyridine core substituted with fluorine and a trimethylsilyl group. This compound is essential for advanced synthetic chemistry, enabling the precise construction of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly for CNS and oncology targets.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and advanced polymers.
• Cross-Coupling Reactions: The silyl group can act as a versatile handle for further functionalization via silicon-based coupling methodologies.
• Fluorine Chemistry: A valuable reagent for introducing fluorine atoms and silyl-protected sites into complex molecular architectures.

Basic Information

Item	Detail
Product Name	Pyridine,3,5-Difluoro-4-(Trimethylsilyl)-(9Ci)
CAS No.	210169-19-0
Molecular Formula	C8H11F2NSi
Molecular Weight	187.27 g/mol
Synonyms	3,5-Difluoro-4-(trimethylsilyl)pyridine; 4-(Trimethylsilyl)-3,5-difluoropyridine; 3,5-Difluoro-4-trimethylsilylpyridine; 3,5-Difluoro-4-pyridyltrimethylsilane; Pyridine, 3,5-difluoro-4-(trimethylsilyl)-; (3,5-Difluoropyridin-4-yl)trimethylsilane
EINECS	Contact for details

Quality Control

Every batch of Pyridine,3,5-Difluoro-4-(Trimethylsilyl)-(9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for critical research and development. We provide comprehensive analytical data including HPLC purity, NMR, and GC-MS to verify identity and quality. Certificates of Analysis (COA) are available for all shipments, and we support custom synthesis to meet specific purity or packaging requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.