Description

n-Butyldeoxynojirimycin, Hydrochloride is a potent and selective glycosidase inhibitor, specifically targeting α-glucosidase I. This compound is a critical research-grade intermediate and active pharmaceutical ingredient (API) for investigating metabolic and lysosomal storage disorders. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of more complex glycosidase inhibitors for therapeutic applications.
• Biochemical Research: Used as a precise tool compound to study N-linked glycosylation pathways and glycoprotein processing in cell biology.
• Therapeutic Agent Development: Investigated for its potential in treating viral infections, including HIV, as well as genetic disorders like Gaucher's disease.
• Enzyme Inhibition Studies: Serves as a reference standard in assays to measure α-glucosidase I and II activity.
• Preclinical Studies: Utilized in animal models to evaluate pharmacokinetics, efficacy, and safety profiles of glycosidase-targeting drugs.

Basic Information

Product Name	n-Butyldeoxynojirimycin, Hydrochloride
CAS No.	210110-90-0
Molecular Formula	C10H20N2O4 • HCl
Molecular Weight	268.74 g/mol (free base: 232.28)
Synonyms	NB-DNJ HCl; N-Butyl-deoxynojirimycin Hydrochloride; 1-Butyl-1,5-dideoxy-1,5-imino-D-glucitol Hydrochloride; (2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol Hydrochloride; Zavesca® Impurity; Miglustat Impurity; ADM-001; SC-48334
EINECS	Contact for details

Quality Control

Our n-Butyldeoxynojirimycin, Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.