Description

2-Amino-3,7,8-Trimethyl-3H-Imidazo[4,5-F]Quinoxaline-2-14C is a carbon-14 labeled isotopologue of a heterocyclic aromatic amine, a critical tool for advanced metabolic and pharmacokinetic studies. This compound matters for researchers requiring precise, high-specific-activity tracers to investigate the formation, distribution, and elimination of related compounds in biological systems. It is primarily needed by pharmaceutical R&D teams, contract research organizations (CROs), and toxicology laboratories focused on food safety and chemical safety assessment.

Application

• Radiolabeled Tracer Studies: Used as a high-specific-activity internal standard in quantitative bioanalysis via liquid chromatography-mass spectrometry (LC-MS).
• Metabolic Pathway Elucidation: Enables detailed tracking of the absorption, distribution, metabolism, and excretion (ADME) profiles of heterocyclic aromatic amines.
• Toxicokinetic Research: Facilitates precise measurement of compound concentrations in plasma, tissues, and excreta for safety assessment.
• Biomarker Development: Supports the development and validation of analytical methods for detecting DNA adducts or metabolite biomarkers.
• Environmental Fate Studies: Applied in research to trace the environmental transformation and persistence of similar complex organic molecules.
• Reference Standard for Method Validation: Serves as an authenticated standard for calibrating analytical instruments and validating assay methods in regulatory submissions.

Basic Information

Product Name	2-Amino-3,7,8-Trimethyl-3H-Imidazo[4,5-F]Quinoxaline-2-14C
CAS No.	210100-53-1
Molecular Formula	C12H1214CN5 *
Molecular Weight	~229.26 g/mol (unlabeled) **
Synonyms	2-Amino-3,7,8-trimethylimidazo[4,5-f]quinoxaline-2-14C
2-14C-2-Amino-3,7,8-trimethyl-3H-imidazo[4,5-f]quinoxaline
Carbon-14 Labeled 2-Amino-3,7,8-trimethylimidazo[4,5-f]quinoxaline
2-14C-ATQ
2-Amino-3,7,8-trimethyl-3H-imidazo[4,5-f]quinoxaline (2-14C)
Radiolabeled IQ-type compound
14C-2-Amino-3,7,8-trimethylimidazoquinoxaline
EINECS	Contact for details

* Formula indicates position of Carbon-14 label. ** Exact molecular weight depends on specific activity and isotopic enrichment; contact for details.

Quality Control

Every batch of our radiolabeled compounds is produced and tested under a strict quality management system. We guarantee high radiochemical purity (>95% by HPLC) and provide full analytical data including specific activity (mCi/mmol or GBq/mmol). A comprehensive Certificate of Analysis (COA) is supplied with each shipment, detailing results for identity (HPLC, MS), radiochemical purity, chemical purity, and specific activity to ensure compliance with research and regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at or below -20°C. The product is light-sensitive (store away from light). Allow the vial to reach ambient temperature before opening to minimize moisture condensation. Store in accordance with local regulations for radioactive materials.

Specification

Item	Specification
Appearance	Solid (color to be specified per batch)
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with structure
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 90%
Specific Activity	50 - 60 mCi/mmol (1.85 - 2.22 GBq/mmol) ***
Solvent (if supplied as solution)	Specified on COA (e.g., Ethanol, Toluene)
Radioactivity Concentration	Specified on COA (μCi/mL or MBq/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

*** Typical range. Exact value is batch-specific and provided on the COA.