Description

3-Amino-1-Methyl-5H-Pyrido[4,3-B]Indole-3-14C, Acetate is a carbon-14 radiolabeled derivative of a heterocyclic amine, specifically designed for advanced research and development applications. This compound is critical for conducting precise metabolic, pharmacokinetic, and environmental fate studies where isotopic tracing is required. It is an essential tool for scientists in pharmaceutical R&D, contract research organizations (CROs), and academic institutions focused on drug discovery and toxicology.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities in preclinical research.
• Metabolic Pathway Elucidation: Enables the detailed mapping of biotransformation pathways and identification of metabolites in in vitro and in vivo systems.
• Environmental Fate and Ecotoxicology Research: Applied in studies to track the degradation, bioaccumulation, and translocation of chemical compounds within environmental matrices.
• Biomolecular Binding Studies: Facilitates research into the binding affinity and interaction mechanisms of compounds with biological targets such as enzymes or receptors.
• Reference Standard for Analytical Method Development: Serves as a critical standard for developing and validating sensitive analytical methods like LC-MS/MS or radio-HPLC.
• Toxicology and Safety Assessment: Supports investigative toxicology studies to understand the formation and role of reactive metabolites.

Basic Information

Item	Detail
Product Name	3-Amino-1-Methyl-5H-Pyrido[4,3-B]Indole-3-14C, Acetate
CAS No.	210049-15-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-Amino-1-methyl-5H-pyrido[4,3-b]indole-3-14C acetate; Trp-P-2-14C, Acetate; 3-Amino-1-methyl-5H-pyrido[4,3-b]indole-3-14C acetic acid salt; 14C-Labeled Trp-P-2 acetate; 1-Methyl-3-amino-5H-pyrido[4,3-b]indole-3-14C acetate; Radiolabeled Heterocyclic Aromatic Amine; Carbon-14 Labeled HAA; [3-14C]-3-Amino-1-methyl-5H-pyrido[4,3-b]indole acetate
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled compounds is manufactured and analyzed under strict quality systems to ensure radiochemical purity, chemical purity, and specific activity meet exacting research standards. Comprehensive analysis is performed using techniques including HPLC with radiometric detection and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific activity, purity, and solvent composition. Our quality commitment supports compliance with GLP (Good Laboratory Practice) guidelines for non-clinical laboratory studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a controlled environment to minimize exposure to moisture. For long-term storage, keep the container in a dedicated, properly labeled freezer.

Specification

Item	Specification
Appearance	Solid (Color to be specified on COA)
Identification (HPLC)	Conforms
Radiochemical Purity (Radiometric HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 95%
Specific Activity	Customized (mCi/mmol)
Solvent	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.