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2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-2-13C CAS NO 209977-58-2
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CAS No.:209977-58-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-2-13C is a stable isotope-labeled analog of the heterocyclic aromatic amine MeIQx, where the carbon at the 2-position is enriched with the 13C isotope. This compound is of critical importance as a high-purity internal standard for accurate quantification and metabolic studies in analytical chemistry and toxicology research. It is primarily needed by research institutions, analytical laboratories, and pharmaceutical companies engaged in food safety testing, carcinogen research, and advanced mass spectrometry (LC-MS/MS, GC-MS) method development.
Application
- Internal Standard for Mass Spectrometry: Serves as a crucial isotopic internal standard for the precise quantification of MeIQx and related compounds in complex matrices using LC-MS/MS and GC-MS.
- Food Safety & Contaminant Analysis: Used in the analysis of heterocyclic aromatic amines (HAAs) in cooked meat products, supporting food safety monitoring and regulatory compliance.
- Metabolic and Pharmacokinetic Studies: Enables tracing and quantification of MeIQx metabolites in in vitro and in vivo studies to understand bioactivation and detoxification pathways.
- Toxicology and Carcinogenesis Research: Facilitates research into the formation, exposure, and biological impact of dietary mutagens and carcinogens.
- Method Development and Validation: Essential for developing, optimizing, and validating highly sensitive and specific analytical methods in accredited laboratories.
- Quality Control & Reference Material: Acts as a certified reference material (CRM) or component in quality control programs for analytical testing services.
Basic Information
| Product Name | 2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-2-13C |
| CAS No. | 209977-58-2 |
| Molecular Formula | C1113CH11N5 |
| Molecular Weight | ~214.2 g/mol |
| Synonyms | MeIQx-2-13C; 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C; 13C-Labeled MeIQx; 2-13C-3,8-Dimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine; Isotopically Labeled MeIQx; [2-13C]-MeIQx; 2-13C-2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline |
| EINECS | Contact for details |
Quality Control
Our 2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-2-13C is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic enrichment, and purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific data is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to ensure long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellow to brown powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Chemical Purity) |
| Isotopic Enrichment | ≥ 99 atom % 13C (at the 2-position) |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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