Description

6-Chloropyridazine-3-Sulfonyl Fluoride is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its core value lies in the reactive sulfonyl fluoride group, which enables efficient and selective transformations under mild conditions, making it a critical reagent for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, chemical biology, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for creating sulfonamide-based pharmacophores with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyridazine scaffold for bioactivity.
• Chemical Biology Probe Development: The sulfonyl fluoride moiety acts as an electrophilic warhead for the covalent modification of proteins, useful in activity-based protein profiling (ABPP) and target identification.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Sulfur(VI) Fluoride Exchange (SuFEx) Chemistry: Functions as a reliable click chemistry hub for constructing stable linkages between molecules, a valuable tool in combinatorial chemistry and bioconjugation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Item	Details
Product Name	6-Chloropyridazine-3-Sulfonyl Fluoride
CAS No.	209848-48-6
Molecular Formula	C4H2ClFN2O2S
Molecular Weight	204.58 g/mol
Synonyms	3-Chloro-6-pyridazinylsulfonyl fluoride; 6-Chloro-3-pyridazinesulfonyl fluoride; 6-Chloro-3-pyridazinylsulfonyl fluoride; 6-Chloropyridazine-3-sulfonylfluoride; 3-Pyridazinesulfonyl fluoride, 6-chloro-; 6-Chloro-1,2-diazine-3-sulfonyl fluoride
EINECS	Contact for details

Quality Control

Our 6-Chloropyridazine-3-Sulfonyl Fluoride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.