Description

4-(2-Thienyl)Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in modern organic synthesis. Its molecular structure, featuring both a thiophene and a benzenesulfonyl chloride group, makes it a valuable building block for constructing more complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the sulfonamide moiety is a common pharmacophore.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, coatings, and specialty materials with specific electronic or mechanical properties.
• Chemical Biology Probes: Employed in the creation of activity-based probes (ABPs) and other research tools for studying enzyme function and protein interactions.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.

Basic Information

Product Name	4-(2-Thienyl)Benzenesulfonyl Chloride
CAS No.	209592-91-6
Molecular Formula	C10H7ClO2S2
Molecular Weight	258.74 g/mol
Synonyms	4-(Thiophen-2-yl)benzenesulfonyl chloride; 2-(4-Chlorosulfonylphenyl)thiophene; 4-(2-Thienyl)phenylsulfonyl chloride; p-(2-Thienyl)benzenesulfonyl chloride; 4-(Thiophene-2-yl)benzene-1-sulfonyl chloride; 2-(4-(Chlorosulfonyl)phenyl)thiophene; Benzenesulfonyl chloride, 4-(2-thienyl)-
EINECS	Contact for details

Quality Control

Our production of 4-(2-Thienyl)Benzenesulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.