Description

S-Methyl-L-Thiocitrulline Dihydrochloride is a high-purity, chemically modified derivative of L-citrulline, specifically designed for advanced biochemical and pharmaceutical research. This compound serves as a potent and selective inhibitor of nitric oxide synthase (NOS), making it a critical tool for studying nitric oxide signaling pathways and related physiological processes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in cardiovascular, neurological, and immunological research.

Application

• Biochemical Research: As a key reagent for investigating the role and inhibition of nitric oxide synthase (NOS) isoforms in cellular and enzymatic assays.
• Pharmaceutical Development: Used in the discovery and preclinical evaluation of novel therapeutics targeting conditions like hypertension, inflammation, and neurodegenerative diseases.
• Academic Research: A standard tool in university laboratories for studying vascular biology, neurotransmission, and immune system regulation.
• Diagnostic Reagent Manufacturing: Potential use as a component in the development of diagnostic kits for measuring NOS activity or related biomarkers.
• Cell Signaling Studies: Employed to modulate NO pathways in cell culture models to understand downstream effects on gene expression and cell function.

Basic Information

Product Name	S-Methyl-L-Thiocitrulline Dihydrochloride
CAS No.	209589-59-3
Molecular Formula	C7H17Cl2N3O2S
Molecular Weight	278.20 g/mol
Synonyms	S-Methyl-L-thiocitrulline dihydrochloride; (2S)-2-Amino-5-[(methylsulfanyl)amino]-5-oxopentanoic acid dihydrochloride; L-Thiocitrulline, S-methyl-, dihydrochloride; S-Methylthiocitrulline dihydrochloride; SMTC dihydrochloride; NOS Inhibitor SMTC; 209589-59-3
EINECS	Contact for details

Quality Control

Every batch of S-Methyl-L-Thiocitrulline Dihydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with our stringent in-house specifications. Our quality commitment supports research reproducibility and meets the demanding standards of the global life sciences industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.