Description

1-Azetidinecarboxylic Acid, 2-[[[2-Fluoro-3-Pyridinyl]oxy]methyl]-, (2S)- is a high-value, chiral azetidine derivative that serves as a critical building block in modern synthetic organic chemistry. Its unique structure, featuring a fluorinated pyridinyloxy side chain, makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and synthesis of new drug candidates, particularly in areas requiring fluorinated heterocycles.
• Agrochemical Development: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and azetidine core can enhance bioavailability and efficacy.
• Chemical Biology Research: Employed as a probe or building block in medicinal chemistry for studying enzyme inhibition and receptor-ligand interactions.
• Process Chemistry & Scale-up: Serves as a starting material for the GMP-compliant production of active substances under controlled conditions.
• Custom Synthesis: A versatile precursor for contract research organizations (CROs) and CDMOs specializing in fluorinated and constrained ring systems.

Basic Information

Item	Detail
Product Name	1-Azetidinecarboxylic Acid, 2-[[[2-Fluoro-3-Pyridinyl]oxy]methyl]-, (2S)-
CAS No.	209530-93-8
Molecular Formula	C10H11FN2O3
Molecular Weight	226.21 g/mol
Synonyms	(2S)-2-[[(2-Fluoro-3-pyridinyl)oxy]methyl]-1-azetidinecarboxylic acid; (S)-2-(((2-Fluoro-3-pyridyl)oxy)methyl)azetidine-1-carboxylic acid; 2-(((2-Fluoro-3-pyridyl)oxy)methyl)azetidine-1-carboxylic acid (S-enantiomer); 1-Azetidinecarboxylic acid, 2-(((2-fluoro-3-pyridinyl)oxy)methyl)-, (2S)-; (S)-2-((2-Fluoro-3-pyridyloxy)methyl)azetidine-1-carboxylic acid; Fluoropyridinyloxy methyl azetidinecarboxylic acid; (S)-enantiomer of the azetidine fluoropyridine derivative.
EINECS	Contact for details

Quality Control

Our production of 1-Azetidinecarboxylic Acid, 2-[[[2-Fluoro-3-Pyridinyl]oxy]methyl]-, (2S)- adheres to stringent quality protocols suitable for advanced intermediate applications. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet exacting customer requirements. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided for every shipment, supporting regulatory filings and process validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.